000			01867nam a2200289 4500
001			ESSALUD
005			20260902161515.0
007			ta
008			t pe ||||| |||| 00| 0 spa d
040			_aBMG
041			_aeng
100			_aAllenbach, Yves _954482
245			_aInflammatory myopathies
300			_apáginas: 1925-1938
520			_aInflammatory myopathies are a heterogeneous group of autoimmune diseases characterized by immune-mediated damage to skeletal muscle. They are classified into five major subtypes: inclusion-body myositis, immune-mediated necrotizing myopathies, antisynthetase syndrome, overlapping myositis, and dermatomyositis, each with distinct clinical features and outcomes. Inclusion-body myositis and immune-mediated necrotizing myopathies primarily affect muscle, with prognosis largely determined by functional impairment, whereas antisynthetase syndrome, overlapping myositis, and dermatomyositis are systemic diseases that can involve the skin, joints, and lungs and may be life-threatening. The majority of inflammatory myopathies are associated with myositis-specific autoantibodies, which inform diagnosis, subtype classification, and prognosis. Advances in understanding the distinct pathomechanisms underlying each subgroup now enable increasingly targeted therapeutic approaches.
650			_aALERGIA _97055
650			_aINMUNOLOGÍA GENERAL _953664
650			_aENFERMEDAD AUTOINMUNE _953665
650			_aENFERMEDAD INFLAMATORIA _953667
650			_aNEUROLOGÍA
650			_aNEUROCIRUGÍA GENERAL _953668
650			_aENFERMEDAD NEUROMUSCULAR _953763
650			_aREUMATOLOGÍA GENERAL _954450
700			_aBenveniste, Olivier _954483
773	0		_022717 _922669 _dMassachusetts NEJM Group _oNEJM014 _tThe New England Journal of Medicine _wESSALUD _x0028-4793
942			_cARTICULOS _e2026-08-31 _zsqb
999			_c22904 _d22904