000 01730nam a2200253 4500
001 ESSALUD
005 20260805002026.0
007 ta
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040 _aBMG
041 _aeng
100 _aDu Toit, George
_eAutor
_953889
245 _aPrevention and treatment of peanut allergy
300 _apáginas: 2449-2458
520 _aEarly introduction of peanut protein reduces allergy prevalence by approximately 80%, with efficacy diminishing as introduction is delayed. Appropriate prevention involves ingestion of approximately 2 g of peanut protein weekly for infants at low risk and 4 to 6 g weekly for infants at high risk. Population-level implementation that targets all infants achieves greater reduction in disease burden than approaches that target only high-risk groups, although disparities exist among some ethnic groups and groups with restricted access to care. Peanut immunotherapy initiated in younger children (1 to 3 years of age) shows superior efficacy and higher rates of clinical remission as compared with immunotherapy initiated in older children. The natural history of untreated peanut allergy follows a trajectory of increasing peanut-specific IgE levels and clinical reactivity over time, underscoring the importance of early intervention during this narrow developmental window.
650 _aALERGIA
_97055
650 _aDERMATOLOGÍA
_97479
650 _aMEDICINA CLINICA
_933681
650 _aENFERMEDADES INFANTILES
_953890
650 _aNUTRICIÓN
700 _aLack, Gideon
_953891
773 0 _022717
_922639
_dMassachusetts NEJM Group
_oNEJM006
_tThe New England Journal of Medicine
_wESSALUD
_x0028-4793
942 _cARTICULOS
_e2026-07-31
_zSQB
999 _c22764
_d22764