01731nam a2200265 4500 ESSALUD 20260903155458.0 ta t pe ||||| |||| 00| 0 spa d BMG eng Fitzgerald, Rebecca C. Autor 54609 Barrett’s Esophagus páginas: 1723-1735 Barrett’s esophagus develops as a result of chronic acid and bile reflux and carries an increased risk of esophageal adenocarcinoma. Because it has no specific symptoms, many patients do not receive a diagnosis or they present with symptoms of gastroesophageal reflux disease and other related risk factors or complications. Diagnosis relies on endoscopic and histopathological findings, including a visible columnar-cell–lined segment measuring at least 1 cm long that contains intestinal metaplasia with goblet cells. Ongoing surveillance focuses on early detection of malignant progression, particularly high-grade dysplasia and early-stage cancer, which allows curative endoscopic treatment and avoids the adverse effects associated with chemotherapy or esophagectomy. Participation in clinical trials is encouraged to improve detection, risk stratification, and management strategies. GASTROENTEROLOGÍA GENERAL 54610 TRATAMIENTOS EN ONCOLOGÍA 53734 CÁNCER DEL TRACTO GASTROINTESTINAL 53776 GERIATRÍA 1852 ENVEJECIMIENTO GENERAL 54554 HEMATOLOGÍA 7422 ONCOLOGÍA GENERAL 54224 22717 22684 Massachusetts NEJM Group NEJM016 The New England Journal of Medicine ESSALUD 0028-4793 ARTICULOS 2026-08-31 sqb 22936 22936