Allenbach, Yves creator Benveniste, Olivier text pe monographic spa eng

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páginas: 1925-1938 Inflammatory myopathies are a heterogeneous group of autoimmune diseases characterized by immune-mediated damage to skeletal muscle. They are classified into five major subtypes: inclusion-body myositis, immune-mediated necrotizing myopathies, antisynthetase syndrome, overlapping myositis, and dermatomyositis, each with distinct clinical features and outcomes. Inclusion-body myositis and immune-mediated necrotizing myopathies primarily affect muscle, with prognosis largely determined by functional impairment, whereas antisynthetase syndrome, overlapping myositis, and dermatomyositis are systemic diseases that can involve the skin, joints, and lungs and may be life-threatening. The majority of inflammatory myopathies are associated with myositis-specific autoantibodies, which inform diagnosis, subtype classification, and prognosis. Advances in understanding the distinct pathomechanisms underlying each subgroup now enable increasingly targeted therapeutic approaches. ALERGIA INMUNOLOGÍA GENERAL ENFERMEDAD AUTOINMUNE ENFERMEDAD INFLAMATORIA NEUROLOGÍA NEUROCIRUGÍA GENERAL ENFERMEDAD NEUROMUSCULAR REUMATOLOGÍA GENERAL Massachusetts NEJM Group NEJM014 0028-4793 ESSALUD BMG 20260902161515.0 ESSALUD