01867nam a2200289 4500 ESSALUD 20260902161515.0 ta t pe ||||| |||| 00| 0 spa d BMG eng Allenbach, Yves 54482 Inflammatory myopathies páginas: 1925-1938 Inflammatory myopathies are a heterogeneous group of autoimmune diseases characterized by immune-mediated damage to skeletal muscle. They are classified into five major subtypes: inclusion-body myositis, immune-mediated necrotizing myopathies, antisynthetase syndrome, overlapping myositis, and dermatomyositis, each with distinct clinical features and outcomes. Inclusion-body myositis and immune-mediated necrotizing myopathies primarily affect muscle, with prognosis largely determined by functional impairment, whereas antisynthetase syndrome, overlapping myositis, and dermatomyositis are systemic diseases that can involve the skin, joints, and lungs and may be life-threatening. The majority of inflammatory myopathies are associated with myositis-specific autoantibodies, which inform diagnosis, subtype classification, and prognosis. Advances in understanding the distinct pathomechanisms underlying each subgroup now enable increasingly targeted therapeutic approaches. ALERGIA 7055 INMUNOLOGÍA GENERAL 53664 ENFERMEDAD AUTOINMUNE 53665 ENFERMEDAD INFLAMATORIA 53667 NEUROLOGÍA NEUROCIRUGÍA GENERAL 53668 ENFERMEDAD NEUROMUSCULAR 53763 REUMATOLOGÍA GENERAL 54450 Benveniste, Olivier 54483 22717 22669 Massachusetts NEJM Group NEJM014 The New England Journal of Medicine ESSALUD 0028-4793 ARTICULOS 2026-08-31 sqb 22904 22904