TY - BOOK AU - Spyropoulos, Alex C. AU - Vedantham, Suresh TI - Advanced Therapy for Intermediate-Risk Pulmonary Embolism KW - ANTICOAGULACIÓN KW - TROMBOEMBOLISMO KW - CARDIOLOGÍA KW - NEUMOLOGÍA KW - MEDICINA CLÍNICA HOSPITALARIA KW - RADIOLOGÍA GENERAL N2 - Pulmonary embolism is the third leading cardiovascular cause of complications and death after myocardial infarction and stroke, with a rising incidence globally. The approach to management of acute pulmonary embolism as a condition to be treated nonsurgically with systemic heparin anticoagulation was established more than 60 years ago. Patients with high-risk pulmonary embolism and cardiogenic shock appear to benefit from early thrombus removal, with rapid reductions in pulmonary obstruction and pulmonary vascular resistance from baseline and a lower risk of death than with anticoagulation alone, but at the cost of a nearly 10% risk of major bleeding ER -