01581nam a2200301 4500 ESSALUD 20260804163623.0 ta t pe ||||| |||| 00| 0 spa d BMG eng Williams, David A. Autor 53761 Fibromyalgia páginas: 267-277 Fibromyalgia is characterized by widespread pain involving any body tissue and typically accompanied by fatigue and problems with sleep, mood, and memory. Fibromyalgia can occur alone or in combination with other chronic overlapping primary pain conditions, or it can be superimposed on other conditions, such as autoimmune disorders (secondary pain). In fibromyalgia, the central nervous system (CNS) is hyperresponsive to sensory stimuli generally. Successful pharmacologic and nonpharmacologic interventions focus on the CNS to support CNS quiescence and a return to homeostasis. Although fibromyalgia is rarely curable, most cases can be well managed in the context of primary care. MEDICINA DEL ADOLESCENTE 5533 MEDICINA CLÍNICA 33681 MEDICINA CLÍNICA AMBULATORIA 53762 ENFERMEDAD NEUROMUSCULAR 53763 ENDOCRINOLOGÍA 36891 NEUROLOGÍA DOLOR PEDIATRÍA 6401 PSIQUIATRÍA 5413 Clauw, Daniel J. 53764 22717 22636 Massachusetts NEJM Group NEJM003 The New England Journal of Medicine ESSALUD 0028-4793 ARTICULOS 2026-07-31 SQB 22740 22740