02948nam a2200313   4500001000800000005001700008007000300025008004100028040000800069041000800077100003000085245007600115300002300191520193000214650003402144650003002178650004302208650003502251650002602286700002402312700002602336700003502362700002602397700002502423700002802448773011002476942003102586999001702617ESSALUD20260804161722.0ta      t        pe ||||| |||| 00| 0 spa d  aBMG  aeng  aChea, Nora eAutor953753  aHealth Care–Associated Infections in U.S. Hospitals, 2023 versus 2015  apáginas: 255-266  aBackground: Prevalence surveys in U.S. hospitals showed that on any given day, 1 of 25 patients had a health care–associated infection in 2011, as compared with 1 of 31 patients in 2015. We repeated the survey in 2023 to assess changes in the prevalence of such infections. Methods: Using established methods, 10 Emerging Infections Program (EIP) sites recruited up to 25 hospitals each. Hospitals selected a survey day between May 1 and September 30, 2023. EIP staff reviewed medical records of randomly selected patients to identify health care–associated infections using National Healthcare Safety Network definitions. We described patient and hospital characteristics, compared the prevalence of health care–associated infections in 2023 and 2015, and estimated the national burden of health care–associated infections in 2023. Results: In 2023, of 13,653 patients in 218 hospitals, 355 (2.6%; 95% confidence interval [CI], 2.3 to 2.9) had at least one health care–associated infection, as compared with 394 of 12,299 patients (3.2%; 95% CI, 2.9 to 3.5) in 199 hospitals in 2015. Approximately 60% of the health care–associated infections were not associated with devices or procedures. Among 151 hospitals in both surveys, patients were less likely to have a health care–associated infection in 2023 than in 2015, after adjustment for other factors (risk ratio, 0.73; 95% CI, 0.63 to 0.85). We estimated that there were 518,000 health care–associated infections (95% CI, 494,500 to 542,000) in U.S. hospitals in 2023. Conclusions: The prevalence of health care–associated infections was lower in 2023 than in 2015, with 1 of 38 patients on any given day having such an infection; however, the burden of health care–associated infections in U.S. hospitals continued to be high. A majority of the health care–associated infections that were identified were not associated with a device or procedure.  aINFECCIONES BACTERIANAS97357  aMEDICINA CLÍNICA933681  aMEDICINA CLÍNICA HOSPITALARIA953754  aENFERMEDADES INFECCIOSAS96776  aSALUD PÚBLICA91652  aLi, Rongxia 953755  aEure, Taniece 953756  aAlkis Ramirez, Rebecca 953757  aNadle, Joelle 953758  aLee, Jane E. 953759  aLehmann, Monica 9537600 022717922636dMassachusetts NEJM GroupoNEJM003tThe New England Journal of Medicine wESSALUDx0028-4793  cARTICULOSe2026-07-31zSQB  c22739d22739