Endovascular therapy for medium-vessel occlusion stroke — Narrowing the target population

Por: Ospel, Johanna MColaborador(es): Hill, Michael DTipo de material: TextoTextoIdioma: Inglés Descripción: páginas: 1955-1957Tema(s): ICTUS | RADIOLOGÍA GENERAL | NEUMOLOGÍA | ENFERMEDAD ARTERIAL PERIFÉRICA Y AÓRTICA | NEUROLOGÍA | GERIATRÍA | MEDICINA DE URGENCIAS | CUIDADOS INTENSIVOS En: The New England Journal of MedicineResumen: One way to classify acute ischemic stroke is by the anatomy of vessel occlusion. Initial randomized trials of endovascular thrombectomy focused on large-vessel occlusions. These proximal occlusions of the intracranial carotid artery or the stem of the middle cerebral artery (MCA) represent the most severe form of anterior circulation ischemic stroke. The large clinical benefit from endovascular thrombectomy is consistent with the patent artery hypothesis and reperfusion associated with intravenous thrombolysis. Reperfusion success after endovascular thrombectomy is now routinely achieved in 90% of patients, but early reperfusion, as measured with computed tomographic (CT) angiography at approximately 2 to 4 hours after treatment with intravenous thrombolysis, occurs in only 35 to 40% of patients with large-vessel occlusions and in 50% of those with more-distal medium-vessel occlusions.
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Colección General NEJM (Navegar estantería) Vol.394, No.19 (2026) Disponible NEJM014

One way to classify acute ischemic stroke is by the anatomy of vessel occlusion. Initial randomized trials of endovascular thrombectomy focused on large-vessel occlusions. These proximal occlusions of the intracranial carotid artery or the stem of the middle cerebral artery (MCA) represent the most severe form of anterior circulation ischemic stroke. The large clinical benefit from endovascular thrombectomy is consistent with the patent artery hypothesis and reperfusion associated with intravenous thrombolysis. Reperfusion success after endovascular thrombectomy is now routinely achieved in 90% of patients, but early reperfusion, as measured with computed tomographic (CT) angiography at approximately 2 to 4 hours after treatment with intravenous thrombolysis, occurs in only 35 to 40% of patients with large-vessel occlusions and in 50% of those with more-distal medium-vessel occlusions.