Left ventricular unloading in high-risk percutaneous coronary intervention (Registro nro. 22920)

000 -Cabecera
Campo de control interno 02659nam a2200301 4500
001 - Número de control
control field ESSALUD
005 - Fecha y hora de la última transacción
Campo de control 20260903101808.0
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
Elementos de Longitud Fija - Información t pe ||||| |||| 00| 0 spa d
040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Perera, Divaka
Rol del Autor Autor
9 (RLIN) 54527
245 ## - Titulo
Titulo Left ventricular unloading in high-risk percutaneous coronary intervention
300 ## - Páginas
Paginación páginas: 1779-1789
520 ## - Resumen
Resumen Background: Complex percutaneous coronary intervention (PCI) in patients with severely impaired left ventricular function carries a high risk of death and complications. Whether percutaneous left ventricular unloading improves outcomes remains unclear. Methods: We randomly assigned 300 patients with severe left ventricular dysfunction and extensive coronary artery disease in a 1:1 ratio to a strategy of elective unloading with a microaxial flow pump or to standard care during planned complex PCI. The primary outcome was a hierarchical composite that included death from any cause, disabling stroke, spontaneous myocardial infarction, hospitalization for cardiovascular causes, or periprocedural myocardial injury at a minimum of 12 months, as analyzed according to a win ratio. Results: A total of 148 patients were assigned to receive a microaxial flow pump and 152 to receive standard care. At a median of 22 months (interquartile range, 16 to 30), 36.6% of pairwise comparisons favored the microaxial flow pump, and 43.0% favored standard care (win ratio, 0.85; 95% confidence interval [CI], 0.63 to 1.15; difference, −6.4 percentage points; P=0.30). Death from any cause occurred in 47 patients in the microaxial-flow-pump group and 33 in the standard-care group (hazard ratio, 1.54; 95% CI, 0.99 to 2.41). There was no material between-group difference in the risk of bleeding or vascular complications. Conclusions: Among patients with severely impaired left ventricular function undergoing complex PCI, elective left ventricular unloading with a microaxial flow pump did not reduce the risk of major adverse clinical outcomes at a minimum of 12 months.<br/><br/>
650 ## - Temas - Descriptores
Temas - Descriptores CARDIOLOGÍA GENERAL
9 (RLIN) 53638
650 ## - Temas - Descriptores
Temas - Descriptores ENFERMEDAD CORONARIA
9 (RLIN) 14895
650 ## - Temas - Descriptores
Temas - Descriptores INFARTO DE MIOCARDIO
9 (RLIN) 13202
650 ## - Temas - Descriptores
Temas - Descriptores SOPORTE CIRCULATORIO MECÁNICO
9 (RLIN) 54520
700 ## - Autor Personal
Autor Personal Ryan, Matthew
9 (RLIN) 54528
700 ## - Autor Personal
Autor Personal Ezad, Saad M.
9 (RLIN) 54529
700 ## - Autor Personal
Autor Personal Khan, Sohail Q.
9 (RLIN) 54530
700 ## - Autor Personal
Autor Personal Webb, Ian
9 (RLIN) 54531
700 ## - Autor Personal
Autor Personal O’Kane, Peter D.
9 (RLIN) 54532
700 ## - Autor Personal
Autor Personal Weerackody, Roshan
9 (RLIN) 54533
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22676
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM015
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-08-31
Catalogador sqb

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