Endovascular Treatment of Medium-Vessel-Occlusion Strokes (Registro nro. 22900)

000 -Cabecera
Campo de control interno 03246nam a2200337 4500
001 - Número de control
control field ESSALUD
005 - Fecha y hora de la última transacción
Campo de control 20260902155800.0
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
Elementos de Longitud Fija - Información t pe ||||| |||| 00| 0 spa d
040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Hu, Wei
9 (RLIN) 54457
245 ## - Titulo
Titulo Endovascular Treatment of Medium-Vessel-Occlusion Strokes
300 ## - Páginas
Paginación páginas: 1894-1904
520 ## - Resumen
Resumen Background: Endovascular thrombectomy for acute ischemic stroke due to medium-vessel occlusion has had varying results across trials. Whether thrombectomy improves functional outcomes in patients with medium-vessel occlusion and moderate-to-severe deficits is unclear. Methods: We conducted an open-label, randomized trial with blinded outcome assessment at 48 centers in China. Eligible patients were adults who presented within 24 hours after the onset of a moderate-to-severe stroke (National Institutes of Health Stroke Scale [NIHSS] score, ≥6; scale, 0 to 42, with higher scores indicating greater neurologic deficits) due to occlusion of a medium vessel. Patients were assigned in a 1:1 ratio to thrombectomy plus medical management (thrombectomy group) or medical management alone (control group). The primary outcome was functional disability as measured by the shift in the modified Rankin scale score (scale, 0 [no disability] to 6 [death]) at 90 days. Violation of the proportional-odds assumption precluded the use of shift in the modified Rankin scale score, so as prespecified, functional independence (modified Rankin scale score of 0, 1, or 2) at 90 days was used as the primary outcome. Safety outcomes were symptomatic intracranial hemorrhage and 90-day mortality. Results: Among 280 patients in the thrombectomy group and 283 in the control group, the median age was 71 years, the median NIHSS score was 10 (range, 3 to 36), and 42.8% were women; 36.6% received intravenous thrombolysis. Functional independence at 90 days was seen in 58.6% of the patients in the thrombectomy group and in 46.6% of those in the control group (adjusted rate ratio, 1.24; 95% confidence interval, 1.07 to 1.44; P=0.004). The incidence of symptomatic intracranial hemorrhage was 4.7% in the thrombectomy group and 2.2% in the control group; 90-day mortality was 11.1% and 10.2%, respectively. Conclusions: Among patients with acute ischemic stroke due to medium-vessel occlusion and moderate-to-severe deficits, thrombectomy led to a greater likelihood of functional independence than medical management alone but also to a higher risk of symptomatic intracranial hemorrhage.
650 ## - Temas - Descriptores
Temas - Descriptores GERIATRÍA
9 (RLIN) 1852
650 ## - Temas - Descriptores
Temas - Descriptores CUIDADOS INTENSIVOS
9 (RLIN) 5208
650 ## - Temas - Descriptores
Temas - Descriptores RADIOLOGÍA GENERAL
9 (RLIN) 54381
650 ## - Temas - Descriptores
Temas - Descriptores ICTUS
9 (RLIN) 54458
650 ## - Temas - Descriptores
Temas - Descriptores ENFERMEDAD ARTERIAL PERIFÉRICA Y AÓRTICA
9 (RLIN) 54459
650 ## - Temas - Descriptores
Temas - Descriptores MEDICINA DE URGENCIAS GENERAL
9 (RLIN) 54078
650 ## - Temas - Descriptores
Temas - Descriptores CARDIOLOGÍA GENERAL
9 (RLIN) 53638
700 ## - Autor Personal
Autor Personal Jing, Xiaozhong
9 (RLIN) 54460
700 ## - Autor Personal
Autor Personal Chen, Zhongjun
9 (RLIN) 54461
700 ## - Autor Personal
Autor Personal Zheng, Jin
9 (RLIN) 54462
700 ## - Autor Personal
Autor Personal Yi, Tingyu
9 (RLIN) 54463
700 ## - Autor Personal
Autor Personal Zheng, Tuanyuan
9 (RLIN) 54464
700 ## - Autor Personal
Autor Personal Li, Zhide
9 (RLIN) 54465
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22669
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM014
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-08-31
Catalogador sqb

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