Decompression with or without Duraplasty for Chiari I and Syringomyelia (Registro nro. 22888)

000 -Cabecera
Campo de control interno 03084nam a2200373 4500
001 - Número de control
control field ESSALUD
005 - Fecha y hora de la última transacción
Campo de control 20260902145039.0
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
Elementos de Longitud Fija - Información t pe ||||| |||| 00| 0 spa d
040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Limbrick, David D.
Rol del Autor Autor
9 (RLIN) 54408
245 ## - Titulo
Titulo Decompression with or without Duraplasty for Chiari I and Syringomyelia
300 ## - Páginas
Paginación páginas: 2015-2025
520 ## - Resumen
Resumen Background: In children with Chiari type I malformation and syringomyelia, neurosurgical posterior fossa decompression (PFD) provides clinical improvement, but whether duraplasty (incising the dura and placing a dural graft) improves outcomes is unclear. Methods: We conducted a multicenter, cluster-randomized, controlled trial of PFD with duraplasty (PFD-D) as compared with PFD alone. Persons 21 years of age or younger with cerebellar tonsillar ectopia of at least 5 mm and a maximum syrinx diameter of 3.0 to 9.9 mm were enrolled at 38 centers. Centers were cluster-randomized: all the participants within each center underwent the same intervention. The primary outcome was surgical complications within 6 months. Secondary outcomes were clinical improvement, syrinx reduction, and repeat decompression at 10 to 24 months and the change in overall health-related quality of life at 6 to 24 months. Results: A total of 162 participants were included in the trial, of whom 78 were assigned to undergo PFD-D and 84 to undergo PFD alone. The percentage of participants with complications within 6 months was 14% with PFD-D and 6% with PFD (adjusted odds ratio, 2.59; 95% confidence interval [CI], 0.86 to 7.84; P=0.11). At 24 months, the percentage of participants with clinical improvement was 58% with PFD-D and 46% with PFD; the mean (±SD) syrinx reduction was 3.08±2.33 mm and 1.22±1.79 mm, respectively; and the percentage of participants with repeat decompression was 3% and 14%. Changes in health-related quality of life were similar in the two groups. Conclusions: The percentage of participants with surgical complications did not differ significantly between those who underwent PFD-D and those who underwent PFD alone. Larger trials are needed to determine the relative benefits and risks of these two procedures.<br/><br/>
650 ## - Temas - Descriptores
Temas - Descriptores ENFERMEDADES INFANTILES
9 (RLIN) 53890
650 ## - Temas - Descriptores
Temas - Descriptores MEDICINA CLÍNICA HOSPITALARIA
9 (RLIN) 53754
650 ## - Temas - Descriptores
Temas - Descriptores ORTOPEDIA GENERAL
9 (RLIN) 54409
650 ## - Temas - Descriptores
Temas - Descriptores PEDIATRÍA GENERAL
9 (RLIN) 54247
650 ## - Temas - Descriptores
Temas - Descriptores TRASTORNOS DE LA COLUMNA VERTEBRAL
9 (RLIN) 54410
650 ## - Temas - Descriptores
Temas - Descriptores NEUROLOGÍA
650 ## - Temas - Descriptores
Temas - Descriptores NEUROCIRUGÍA GENERAL
9 (RLIN) 53668
700 ## - Autor Personal
Autor Personal Shannon, Chevis N.
9 (RLIN) 54411
700 ## - Autor Personal
Autor Personal Bayman, Emine O.
9 (RLIN) 54412
700 ## - Autor Personal
Autor Personal Meehan, Thanda
9 (RLIN) 54413
700 ## - Autor Personal
Autor Personal Kallem, Marisa
9 (RLIN) 54414
700 ## - Autor Personal
Autor Personal Ackerman, Laurie L.
9 (RLIN) 54415
700 ## - Autor Personal
Autor Personal Adelson, P. David
9 (RLIN) 54416
700 ## - Autor Personal
Autor Personal Ahmed, Raheel
9 (RLIN) 54417
700 ## - Autor Personal
Autor Personal Albert, Gregory
9 (RLIN) 54418
700 ## - Autor Personal
Autor Personal Aldana, Philipp R.
9 (RLIN) 54419
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22665
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM013
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-08-28
Catalogador sqb

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