High-flow or standard oxygen in acute hypoxemic respiratory failure (Registro nro. 22834)

000 -Cabecera
Campo de control interno 02780nam a2200325 4500
001 - Número de control
control field ESSALUD
005 - Fecha y hora de la última transacción
Campo de control 20260819164758.0
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
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040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Frat, Jean-Pierre
Rol del Autor Autor
9 (RLIN) 54172
245 ## - Titulo
Titulo High-flow or standard oxygen in acute hypoxemic respiratory failure
300 ## - Páginas
Paginación páginas: 2095-2106
520 ## - Resumen
Resumen Background: Data are needed on the effect of oxygen delivered through a high-flow nasal cannula, as compared with standard oxygen therapy, on intubation and mortality in patients with acute hypoxemic respiratory failure. Methods: In this multicenter, open-label trial, we randomly assigned patients who had acute hypoxemic respiratory failure to receive high-flow-oxygen or standard-oxygen therapy. All the patients had a ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen of 200 or less, a respiratory rate of more than 25 breaths per minute, and pulmonary infiltrate on chest imaging. The primary outcome was death by day 28. Results: A total of 1116 patients underwent randomization. Of these patients, 1110 (556 in the high-flow-oxygen group and 554 in the standard-oxygen group) were included in the analysis. Mortality at day 28 was 14.6% (in 81 of 556 patients) in the high-flow-oxygen group and 14.6% (in 81 of 554 patients) in the standard-oxygen group (difference, −0.05 percentage points; 95% confidence interval [CI], −4.21 to 4.10; P=0.98). The incidence of intubation by day 28 was 42.4% (in 236 of 556 patients) in the high-flow-oxygen group and 48.4% (in 268 of 554 patients) in the standard-oxygen group (difference, −5.93 percentage points; 95% CI, −11.78 to −0.08). Serious adverse events (cardiac arrest or pneumothorax) occurred during spontaneous breathing in 13 patients (2.3%) in the high-flow-oxygen group and in 6 patients (1.1%) in the standard-oxygen group. Conclusions: Among patients with acute hypoxemic respiratory failure, the use of oxygen delivered through a high-flow nasal cannula did not significantly reduce mortality at day 28.
650 ## - Temas - Descriptores
Temas - Descriptores CUIDADOS INTENSIVOS
9 (RLIN) 5208
650 ## - Temas - Descriptores
Temas - Descriptores MEDICINA DE URGENCIAS
9 (RLIN) 53820
650 ## - Temas - Descriptores
Temas - Descriptores MEDICINA CLINICA HOSPITALARIA
9 (RLIN) 53754
650 ## - Temas - Descriptores
Temas - Descriptores VENTILACION MECANICA
9 (RLIN) 37360
650 ## - Temas - Descriptores
Temas - Descriptores NEUMOLOGÍA
9 (RLIN) 25628
700 ## - Autor Personal
Autor Personal Quenot, Jean-Pierre
9 (RLIN) 54173
700 ## - Autor Personal
Autor Personal Guitton, Christophe
9 (RLIN) 54174
700 ## - Autor Personal
Autor Personal Coudroy, Rémi
9 (RLIN) 54175
700 ## - Autor Personal
Autor Personal Gacouin, Arnaud
9 (RLIN) 54176
700 ## - Autor Personal
Autor Personal Badie, Julio
9 (RLIN) 54177
700 ## - Autor Personal
Autor Personal Demoule, Alexandre
9 (RLIN) 54178
700 ## - Autor Personal
Autor Personal Contou, Damien
9 (RLIN) 54179
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22648
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM011
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-08-19
Catalogador sqb

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