Intravascular ultrasound–guided or angiography-Guided complex High-Risk PCI (Registro nro. 22775)

000 -Cabecera
Campo de control interno 03102nam a2200265 4500
001 - Número de control
control field ESSALUD
005 - Fecha y hora de la última transacción
Campo de control 20260805113310.0
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
Elementos de Longitud Fija - Información t pe ||||| |||| 00| 0 spa d
040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Diletti, Roberto
Rol del Autor Autor
9 (RLIN) 46845
245 ## - Titulo
Titulo Intravascular ultrasound–guided or angiography-Guided complex High-Risk PCI
300 ## - Páginas
Paginación páginas: 2200-2211
520 ## - Resumen
Resumen Background: Intravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) has been associated with increased stent optimization and reduced adverse events among patients with complex coronary-artery lesions, but adoption of this strategy in Western countries remains low. Although practice guidelines recommend intracoronary imaging for anatomically complex lesions, evidence from current European practice is limited. Methods: In this investigator-initiated, international, open-label, randomized, controlled trial, we assigned patients undergoing complex PCI to either IVUS-guided PCI, performed with the use of prespecified stent-optimization criteria, or angiography-guided PCI. The primary end point was target-vessel failure, defined as a composite of death from cardiac causes, target-vessel myocardial infarction, or clinically indicated target-vessel revascularization. Results: Of the 2020 patients who underwent randomization, 1010 in the IVUS-guided PCI group and 1009 in the angiography-guided PCI group were included in the primary analysis. The mean age of the patients was 69 years, 79.4% were men, and 27.4% presented with an acute coronary syndrome. The mean procedure duration was 88.8 minutes with IVUS-guided PCI and 66.2 minutes with angiography-guided PCI. Dilation with balloon angioplasty after stent implantation was performed in 91.3% of the IVUS-guided PCI procedures and in 84.5% of the angiography-guided PCI procedures. At a median follow-up of 19.0 months (interquartile range, 15.2 to 23.4), target-vessel failure had occurred in 140 patients (13.9%) in the IVUS-guided PCI group and in 112 patients (11.1%) in the angiography-guided PCI group (hazard ratio, 1.25; 95% confidence interval, 0.97 to 1.60; P=0.08). Procedural complications occurred in 11.3% of the IVUS-guided PCI procedures and in 10.2% of the angiography-guided PCI procedures. The frequency of adverse events appeared to be similar in the two groups. Conclusions: Among patients undergoing complex high-risk PCI, a strategy of routine IVUS-guided PCI performed with the use of prespecified stent-optimization criteria was not associated with a lower risk of target-vessel failure than angiography-guided PCI alone.
650 ## - Temas - Descriptores
Temas - Descriptores CARDIOLOGIA
9 (RLIN) 11301
650 ## - Temas - Descriptores
Temas - Descriptores ENFERMEDAD CORONARIA
9 (RLIN) 14895
650 ## - Temas - Descriptores
Temas - Descriptores INFARTO DE MIOCARDIO
9 (RLIN) 13202
700 ## - Autor Personal
Autor Personal Daemen, Joost
9 (RLIN) 53647
700 ## - Autor Personal
Autor Personal Faurie, Benjamin
9 (RLIN) 53932
700 ## - Autor Personal
Autor Personal Barbierato, Marco
9 (RLIN) 53649
700 ## - Autor Personal
Autor Personal Tchétché, Didier
9 (RLIN) 53933
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22641
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM008
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-08-03
Catalogador SQB

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