Prehospital resuscitation with type o whole blood for trauma and hemorrhage (Registro nro. 22768)

000 -Cabecera
Campo de control interno 02707nam a2200301 4500
001 - Número de control
control field ESSALUD
005 - Fecha y hora de la última transacción
Campo de control 20260805094732.0
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
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040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Sperry, Jason L
Rol del Autor Autor
9 (RLIN) 53909
245 ## - Titulo
Titulo Prehospital resuscitation with type o whole blood for trauma and hemorrhage
300 ## - Páginas
Paginación páginas: 23017-2328
520 ## - Resumen
Resumen Background: Blood transfusion before arrival at a hospital reduces mortality from traumatic hemorrhage and shock. Whether transfusion with whole blood is more beneficial than transfusion with blood components is uncertain, as are the effects of the length of time that blood products are in storage between donation and transfusion.<br/>Methods: In this pragmatic, multicenter, phase 3, cluster-randomized trial, we assigned 44 air medical bases in a 2:1 ratio to the use of up to 2 units of whole blood or as-indicated blood components (plasma, red cells, or both) for prehospital transfusion in trauma patients during 1-month blocks. The primary outcome was death from any cause within 30 days after randomization. An observational substudy assessed outcomes according to the storage age of whole blood.<br/>Results: Of 1020 eligible patients transported to hospitals by the air bases, 715 were assigned to receive whole blood and 305 to receive blood components; 695 and 298, respectively, were included in the primary analysis. Mortality at 30 days was 25.9% in the whole-blood group and 20.5% in the component group (adjusted odds ratio, 1.24; 95% confidence interval [CI], 0.87 to 1.76; P=0.24). No substantial between-group differences in adverse events were observed. In the observational substudy, 30-day mortality was 27.1% among 210 patients who received whole blood with a storage age of 15 to 21 days and 26.4% among 443 patients who received whole blood with a storage age of 1 to 14 days (adjusted odds ratio, 0.99; 95% CI, 0.74 to 1.32).<br/>Conclusions: In injured patients with hemorrhagic shock, the use of whole blood for prehospital transfusion did not result in lower 30-day mortality than the use of blood components. <br/>
650 ## - Temas - Descriptores
Temas - Descriptores NEUMOLOGÍA
9 (RLIN) 25628
650 ## - Temas - Descriptores
Temas - Descriptores CUIDADOS INTENSIVOS
9 (RLIN) 5208
650 ## - Temas - Descriptores
Temas - Descriptores MEDICINA DE URGENCIAS
9 (RLIN) 53820
650 ## - Temas - Descriptores
Temas - Descriptores HEMATOLOGÍA
9 (RLIN) 7422
650 ## - Temas - Descriptores
Temas - Descriptores MEDICINA CLÍNICA
9 (RLIN) 33681
650 ## - Temas - Descriptores
Temas - Descriptores CHOQUE
9 (RLIN) 44162
700 ## - Autor Personal
Autor Personal Guyette, Francis X.
9 (RLIN) 53910
700 ## - Autor Personal
Autor Personal Cotton, Bryan A.
9 (RLIN) 53911
700 ## - Autor Personal
Autor Personal Luther, James F.
9 (RLIN) 53912
700 ## - Autor Personal
Autor Personal Utarnachitt, Richard B.
9 (RLIN) 53913
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22640
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM007
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-08-03
Catalogador SQB

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