Antiretroviral Therapy (Registro nro. 22748)

000 -Cabecera
Campo de control interno 02231nam a2200205 4500
001 - Número de control
control field ESSALUD
007 - Tipo material - Descripcion fisica - info general
Tipo material - Descripcion fisica - info general ta
008 - Elementos de Longitud Fija - Información General
Elementos de Longitud Fija - Información t pe ||||| |||| 00| 0 spa d
040 ## - Origen de la Catalogación
Origen de la Catalogación BMG
041 ## - Idioma
Idioma eng
100 ## - Autor
Autor Gulick, Roy M.
Rol del Autor Autor
9 (RLIN) 53802
245 ## - Titulo
Titulo Antiretroviral Therapy
300 ## - Páginas
Paginación páginas: 374-387
520 ## - Resumen
Resumen The development of effective treatment strategies for human immunodeficiency virus (HIV) infection is a major achievement. Antiretroviral drugs inhibit key steps in the viral replication cycle and consist of six mechanistic classes: HIV entry inhibitors, reverse-transcriptase inhibitors (both nucleosides and nonnucleosides), capsid inhibitors, integrase inhibitors, and protease inhibitors. Antiretroviral therapy (ART) suppresses viral replication, thereby enhancing immune function, decreasing morbidity and mortality, and preventing viral transmission. Consequently, ART is recommended for all persons with HIV infection. On the basis of randomized clinical trials, the Food and Drug Administration has approved 36 antiretroviral drugs for the treatment of HIV infection since 1987; of these, 28 are currently available in the United States, and combination ART regimens are used. Initial preferred ART regimens are potent, convenient, and unlikely to cause side effects and consist of an HIV integrase inhibitor with a high barrier to resistance combined with one or two nucleoside reverse-transcriptase inhibitors. In the majority of patients using current ART regimens, viral replication is durably suppressed below detectable levels. Patients receiving ART are monitored for virologic response over time, and if virologic failure occurs, the next regimen is selected on the basis of treatment history and the results of drug-resistance testing; often, antiretroviral drugs from new classes are administered. Today, the life expectancy of someone with HIV infection who consistently takes ART approaches that of the general population.
650 ## - Temas - Descriptores
Temas - Descriptores CARDIOLOGÍA
9 (RLIN) 11301
650 ## - Temas - Descriptores
Temas - Descriptores SALUD GLOBAL
9 (RLIN) 10472
650 ## - Temas - Descriptores
Temas - Descriptores VIH/SIDA
9 (RLIN) 53790
773 0# - Revista (Relacion con el numero)
Host Biblionumber 22717
Host Itemnumber 22637
Ciudad, Editorial Massachusetts NEJM Group
Codigo barras item/ejemplar NEJM004
Titulo de la Revista The New England Journal of Medicine
Número de control de registro ESSALUD
ISSN 0028-4793
942 ## - Elementos de Koha
Tipo de Documento Artículos
Fecha procesamiento 2026-07-31
Catalogador SQB

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